منابع مشابه
Tumoral Markers in Prostate Cancer
In Mexico, in 70% of cases, the prostate cancer (PCa) is found in advanced stage. PCa currently occupies second place in frequency of cancer in men, surpassed only by skin cancer, and is the second principal cause of death in men after of lung cancer (Hall et al., 2005). Reactive oxygen species (ROS) such as superoxide (O2 −) and hydrogen peroxide (H2O2) are found in a large number of tumors a...
متن کاملUrine markers and prostate cancer
Prostate cancer (PCa) is globally the most common cancer in men, with an estimated prevalence of more than two million cases. Given the poor success rate in treating advanced PCa, intervention in early stages may reduce the progression of a small, localized carcinoma to a large metastatic lesion, thereby reducing disease-related deaths. Urine is readily available and can be used to detect eithe...
متن کاملMethylation Markers for Prostate Cancer
wnloaded s perspective on Ibragimova et al. (beginning on page 1084 in this issue of the journal) highlights tential role of DNA methylation–based markers in the early detection of prostate cancer (PCa), a focus on the global reactivation of expression of genes epigenetically silenced in PCa cell Novel findings of these investigators identified four genes methylated specifically in PCa, include...
متن کاملPrognostic DNA Methylation Markers for Prostate Cancer
Prostate cancer (PC) is the most commonly diagnosed neoplasm and the third most common cause of cancer-related death amongst men in the Western world. PC is a clinically highly heterogeneous disease, and distinction between aggressive and indolent disease is a major challenge for the management of PC. Currently, no biomarkers or prognostic tools are able to accurately predict tumor progression ...
متن کاملMolecular markers and death from prostate cancer.
BACKGROUND Current methods to assess the prognosis of prostate cancer at the time of diagnosis are limited. OBJECTIVE To determine whether molecular markers of cell cycle regulation (bcl-2 and p53) and angiogenesis (beta-3 integrin, vascular endothelial growth factor, and microvessel density) are associated with increased long-term risk for death among men with prostate cancer. DESIGN Obser...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Genome Biology
سال: 2001
ISSN: 1465-6906
DOI: 10.1186/gb-spotlight-20010823-01